Evidence-based information on hair loss
Hair loss is not a single disease. Androgenetic hair loss, telogen effluvium, alopecia areata, scalp diseases, certain medications, and conditions related to nutrition or systemic diseases require different assessments and treatments.
How is the assessment performed?
The history covers the onset, duration, and distribution of hair loss, family history, diseases, medications, and accompanying symptoms. A scalp examination and, when necessary, dermoscopy are performed. The same panel of laboratory tests is not used for everyone; tests are selected according to the clinical findings. Early physician assessment is required if there is sudden or patchy hair loss, loss of the eyebrows or eyelashes, scalp pain, redness, crusting, or scarring.
Treatment selection
Treatment is planned according to the identified cause. Evidence-based medication options and supportive procedures do not have the same level of evidence for male- and female-pattern hair loss. A 2024 systematic review of PRP reported increased hair density in some studies; however, it emphasized that no definite conclusion could be drawn because of the low quality of evidence, differences in methods, and heterogeneity. Promising permanent results in a single session or for everyone is not scientific.
Possible risks
Injection-based procedures may cause pain, bruising, swelling, headache, and infection. Contraindications and adverse effects of medical treatments are assessed separately for each person.
This text is intended for general information and is not personalized diagnostic or treatment advice.
References
- Blume-Peytavi U, et al. S1 guideline for diagnostic evaluation in androgenetic alopecia in men, women and adolescents. Br J Dermatol. 2011;164(1):5-15. PMID: 20795997. DOI: 10.1111/j.1365-2133.2010.10011.x.
- Donnelly C, et al. The role of platelet-rich plasma in androgenetic alopecia: A systematic review. J Cosmet Dermatol. 2024;23(5):1551-1559. PMID: 38284294. DOI: 10.1111/jocd.16185.
