Evidence-based information on mesotherapy
Mesotherapy describes a procedure in which selected substances are delivered into the superficial or middle layers of the skin through multiple small injections. Its effects and safety depend on the contents of the product used, the indication, the dose, and the application method; the term ‘mesotherapy’ alone does not establish a specific effect.
Available publications show substantial differences among procedures and do not provide standardized, high-quality evidence for every aesthetic purpose. Pain, redness, bruising, swelling, infection, allergic reaction, nodules, pigment changes, and, rarely, tissue damage may be reported. The authorization status and contents of the product to be used, as well as the person’s health status, should be assessed separately.
This text is intended for general information and is not personalized diagnostic or treatment advice. Eligibility is determined after a medical history and examination. Outcomes may vary from person to person; a specific result cannot be guaranteed.
References
- Plachouri KM, et al. Mesotherapy: safety profile and management of complications. J Cosmet Dermatol. 2019. PMID: 31444843. DOI: 10.1111/jocd.13115.
- Mammucari M, et al. International Consensus Guidelines on the Safe and Evidence-Based Practice of Mesotherapy. Curr Med Chem. 2025. PMID: 40649062.
