Evidence-based information on PRP procedures
PRP (platelet-rich plasma) is plasma prepared from a person’s own blood with an increased platelet concentration and applied to selected areas. Because preparation systems and application protocols differ substantially, research findings cannot be generalized directly to every product and protocol.
Evidence for hair loss
A 2024 systematic review of male-pattern androgenetic hair loss reported increased hair density in some studies; however, it noted that the studies were small, the methods differed, and the quality of evidence was low. PRP is not a method proven to provide definite results for every type of hair loss. The cause of hair loss should be assessed first.
Evidence for skin procedures
An overview of systematic reviews examining PRP for facial rejuvenation reported that the available evidence was insufficient to reach a definite conclusion. Uncertainty remains particularly regarding the effect of PRP alone, the most appropriate protocol, and long-term outcomes.
Possible risks and eligibility
Pain, tenderness, bruising, swelling, and headache may occur at the injection site. Infection, tissue damage, or non-allergic inflammatory reactions are less common. Active infection, certain blood and platelet disorders, serious systemic diseases, pregnancy/breastfeeding, and medications that affect bleeding should be assessed separately. Eligibility is determined after a medical history and examination.
This text is intended for general information and is not personalized diagnostic or treatment advice.
References
- Donnelly C, et al. The role of platelet-rich plasma in androgenetic alopecia: A systematic review. J Cosmet Dermatol. 2024;23(5):1551-1559. PMID: 38284294. DOI: 10.1111/jocd.16185.
- Cruciani M, et al. Platelet rich plasma for facial rejuvenation: an overview of systematic reviews. Blood Transfus. 2024;22(5):429-439. PMID: 38557322. DOI: 10.2450/BloodTransfus.730.
